Cell BiologybioRxivPreprint
Dysregulation of the engulfment pathway in the gut fuels Inflammatory Bowel Disease
Katherine Suarez, Eileen Lim, Sujay Singh…·Soumita Das
This study shows that ELMO1 dysregulation in the gut epithelium and macrophages contributes to IBD by promoting bacterial internalization and pro-inflammatory cytokine production.
DOI 10.1101/280172