Author

Ye Chen

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Baicheng Cheng· 1 shared Bin Zhao· 1 shared Bing XuiD· 1 shared C H I ZhangiD· 1 shared Can Yang ZhangiD· 1 shared Canrong LiiD· 1 shared Cha LiniD· 1 shared Chen Wang· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

Baicheng Cheng

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Deanticoagulated heparins drive a novel repair-secretory epithelial program to restore mucosal barrier in ulcerative colitis

Wei Hu, Zhen Kang Liu, Long Huang, Wen Zeng, Xiao Yi Ren, Yang Ji, Zheng Yang Song, Qin Xuan Zhou, Hai Hong Chen, Bing Xu, Can Yang Zhang, Chong Zhang, Peter Edward Lobie, Zhen Qing Zhang, Yun Sheng Yang, , Xin‐Hui Xing

The paper identifies NALHP/S6, a heparin derivative, as a glycan-based modulator that restores mucosal barrier function in ulcerative colitis by promoting a repair-secretory epithelial state.

bioRxiv · Aug 24, 2026 · PreprintMolecular Biology

AMPKγ2 Deacetylation Drives Nuclear Translocation and Doxorubicin-Induced Cardiomyopathy via Nucleolar Stress Signaling

Canrong Li, Tiantian Yi, Y M Cui, Baicheng Cheng, Juan Lan, C H I Zhang, Cha Lin, F Y Yang, Ye Chen, X Wang, Hong Peng, Bin Zhao, Leping Yan, Hor‐Yue Tan, Xiaoduo Xie

This study identifies AMPKγ2 deacetylation as a driver of Doxorubicin-induced cardiomyopathy through nucleolar stress and p53-mediated apoptosis, suggesting HDAC inhibitors could mitigate cardiac toxicity.

bioRxiv · Jul 16, 2026 · PreprintCell Biology

Volume regulation of cancer cells during osmotic pressure variation

Xiapeng Wang, Jiarui Gan, Wenjie Wu, Shubo Zhang, Ting Zhang, Chen Wang, Ye Chen, Qingchuan Zhang, Shangquan Wu

This study compares how cancer and normal cells respond to osmotic pressure changes, finding cancer cells recover volume and traction forces more slowly under hypotonic conditions.

bioRxiv · Mar 11, 2026 · PreprintBiophysics

Biodegradable Poly(β-amino amide)s Enable Efficient RNA Delivery and Spleen Targeting

Xuejin Yang, Jingya Xiao, Yajie Zhai, Leqi Liao, Han Qiu, Ye Chen, Daryl Staveness, Xiaoyu Zang

This paper develops biodegradable PBAA polymers for efficient RNA delivery and spleen targeting, achieving high gene editing efficiency and stability.

bioRxiv · Mar 3, 2025 · PreprintBiochemistry

Decoding dynamic visual scenes across the brain hierarchy

Ye Chen, Peter Beech, Ziwei Yin, Shanshan Jia, Jiayi Zhang, Zhaofei Yu, Jian K. Liu

This study uses deep learning to decode dynamic natural visual scenes from neural activity across brain regions, revealing distinct encoding patterns in visual cortex and subcortical nuclei compared to hippocampus.

PLoS Computational Biology · Aug 2, 2024Peer-reviewedNeuroscience