Can Yang Zhang

The paper identifies NALHP/S6, a heparin derivative, as a glycan-based modulator that restores mucosal barrier function in ulcerative colitis by promoting a repair-secretory epithelial state.

This paper develops a probiotic system for ulcerative colitis that enhances probiotic survival and colon targeting, modulates gut microbiota and immune responses, and provides a mathematical model for release dynamics.

This paper develops an oral nanotherapeutic, OPNs@LMWH, that targets intestinal integrins and regulates redox homeostasis to treat ulcerative colitis, showing improved therapeutic efficacy and immune uptake.

This paper develops a rapid, sensitive, and point-of-care FV3 detection system combining RPA-CRISPR/Cas12a with smartphone microscopy and deep learning, achieving 100% accuracy in classification.