NeuroscienceCell Death and DiseasePeer-reviewed
Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells
Genea Edwards, Guy A Perkins, Keun-young Kim A…·Won‐Kyu Ju
This study shows that loss of AKAP1 leads to Drp1 dephosphorylation, mitochondrial fragmentation, and RGC dysfunction in glaucoma, suggesting AKAP1 as a therapeutic target.
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