NeurosciencebioRxivPreprint
Protecting synapses from amyloid β-associated degeneration by manipulations of Wnt/planar cell polarity signaling
Bo Feng, Andiara E. Freitas, Runyi Tian…·Yimin Zou
The paper investigates how Aβ oligomers disrupt Wnt/PCP signaling by interacting with Celsr3 and Vangl2, leading to synapse loss in Alzheimer's disease, and suggests potential therapeutic strategies.
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