Yibo Xuan

The paper proposes a negative feedback model explaining SARS-CoV-2 replication and transcription regulation through nsp15 cleavage of transcription regulatory sequences.

The paper uses small RNA sequencing to obtain the full-length genome sequence of a novel tick-borne flavivirus and demonstrates the feasibility of using sRNA-seq for virus detection in low-RNA samples.

The paper annotates tick mitochondrial genomes using long-PCR and NGS, revealing novel STR variation and a transposon-like element, and links STR mutations to aging and disease.