Author

Yilin Chen

Tulane University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jay K. KollsiD· 3 shared Xiaofeng DingiD· 3 shared Jefferson Fernandes EvangelistaiD· 2 shared Mohammad IslamuddiniD· 2 shared Robert V. BlairiD· 2 shared Xuebin QiniD· 2 shared Ahmad A. SaiediD· 1 shared Amrita Kumar· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

Jay K. KollsORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IRF7 deficiency increases disease severity independently of TLR7 recognition in Influenza A infection in mice

Ana Karina Nisperuza Vidal, Chenxiao Wang, Michaela J. Allen, Xiaofeng Ding, Jefferson Fernandes Evangelista, Yilin Chen, M Khatun, Amrita Kumar, Calder R. Ellsworth, Mohammad Islamuddin, Robert V. Blair, Suryaprakash R. Sambhara, Jay K. Kolls, Derek A. Pociask, Xuebin Qin

This study shows that IRF7 deficiency worsens influenza A disease in mice, independent of TLR7, by impairing early interferon responses and adaptive immunity.

bioRxiv · May 26, 2026 · PreprintImmunology

Rapid Podocyte ablation Causes Acute Renal Tubule Cell Necrosis and Interstitial Fibrosis

Yilin Chen, Mohammad Islamuddin, Xiaofeng Ding, Jefferson Fernandes Evangelista, Avi Salomon, Gabriella M Hidalgo, Shumei Liu, Cecily C. Midkiff, Ryousuke Satou, Jia L. Zhuo, Jay K. Kolls, Vecihi Batuman, Rhea Bhargava, Robert V Blair, Xuebin Qin

This study uses a mouse model to show that rapid podocyte ablation leads to acute renal tubule cell necrosis, interstitial fibrosis, and renal failure.

bioRxiv · Mar 23, 2026 · PreprintPathology

Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART

Yilin Chen, Xiaofeng Ding, Sonalika Ray, Siva Thirugnanam, Robert V. Blair, Ahmad A. Saied, Sergiy Sukhanov, Jay K. Kolls, W. Y. KIM, Patrice Delafontaine, Jay Rappaport, Xuebin Qin, Namita Rout

This study shows that long-term ART in SIV-infected macaques reduces acute inflammation but maintains chronic macrophage and TLR-driven inflammation linked to vascular damage and aging.

Frontiers in Immunology · Mar 12, 2026Peer-reviewedImmunology

Assessing Generative Model Coverage of Protein Structures with SHAPES

Tianyu Lu, Melissa Liu, Yilin Chen, Jinho Kim, Po‐Ssu Huang

This study evaluates generative models of protein structures using SHAPES, revealing undersampling of structural motifs and highlighting the need for better design and prediction methods.

Cell Systems · Jan 14, 2025Peer-reviewedBioengineering