Cell BiologybioRxiv
Lipid metabolic perturbation is an early-onset phenotype in adult spin mutants: a Drosophila model for lysosomal storage disorders
sarita hebbar, Avinash Khandelwal, Jayashree R…·Dominik Schwudke
This study identifies lipid metabolic imbalances in Drosophila spin mutants, linking ceramide/sphingosine homeostasis to early neurodegeneration in lysosomal storage disorders.
DOI 10.1091/mbc.e16-09-0674