Developmental BiologyDevelopmentPeer-reviewed
Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse
Yinan Zhao, Dandan Bai, You Wu…·Zhongxian Lu
This study shows that maternal Ezh1/2 deficiency disrupts H3K27 methylation in oocytes, leading to delayed restoration and impaired epiblast development, causing embryonic sub-lethality in mice.
25 citations