BioengineeringStem Cell Research & TherapyPeer-reviewed
Engineering a Controlled Cardiac Multilineage Co-Differentiation Process Using Statistical Design of Experiments
Hirokazu Akiyama, Yosuke Katayama, Kazunori Shimizu, Hiroyuki Honda
This study engineers a controlled cardiac multilineage co-differentiation process using statistical design of experiments to generate cardiomyocytes, mural cells, and endothelial cells from iPSCs with high controllability and maturity.
DOI 10.1186/s13287-025-04408-0