Author

Lili Zhu

East China University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Honglin LiiD· 3 shared Jiawen Wang· 2 shared Mengzhu Xue· 2 shared Shanshan Ruan· 2 shared Shiliang LiiD· 2 shared Tianyu Ye· 2 shared Asuka InoueiD· 1 shared Bernard OfosuheneiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiochemistry

Honglin LiORCID

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Author profile →

3 papers

Recent·Most cited

Pharmacology & ToxicologyCirculation ResearchPeer-reviewedMar 20, 2026

Inhibiting RhoA Activation via GDP-state Stabilization to Relieve Heart Failure

Mengzhu Xue, Yingquan Liang, Zhen Yuan…·Honglin Li

This study identifies a compound that inhibits RhoA activation by stabilizing its GDP state, reducing myocardial remodeling and fibrosis in heart failure models.

3 citationstop 1%

mouseproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintJan 5, 2026

TRPV4 Inhibition by a Natural Product Mediates Analgesia

Zhen Yuan, Jie Qiu, Shiliang Li…·Bowen Ke

This study identifies AH001 as a potent TRPV4 inhibitor, revealing its mechanism and demonstrating its analgesic effects in pain models.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiochemistrybioRxivPreprintMar 2, 2024

Structural insights into sphingosine 1-phosphate receptor 4 activation

Wei Gao, Shiyi Gan, Mengting Zhang…·Honglin Li

The paper determines the cryo-EM structure of activated S1PR4, revealing mechanisms of ligand recognition and Gi coupling to aid in developing safer S1PR4 agonists.

1 citation

humancryo-EM

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