Author
The University of Texas MD Anderson Cancer Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Richard F. Lyman, Vijay Shankar, Rachel A. Lyman…·Trudy F. C. Mackay
The paper introduces DGRP3, an expanded Drosophila genetic reference panel with 1,233 inbred lines, identifying genetic variants and performing GWAS for traits like inbreeding depression and sensory bristles.
Vakul Mohanty, Natalia Baran, Yuefan Huang…·Ken Chen
This study identifies four transcriptionally distinct venetoclax-resistant clusters in AML, revealing phenotypic, genetic, and drug response differences and their implications for treatment resistance.
Qingnan Liang, Yuefan Huang, Shan He, Ken Chen
GSDensity provides pathway-centric analysis of single-cell and spatial transcriptomics data without clustering, revealing novel cell-pathway associations and spatially relevant pathways in cancer and brain development.
Yuefan Huang, Vakul Mohanty, Merve Dede…·Ken Chen
The paper develops METAFlux to infer metabolic fluxes from bulk and single-cell RNA-seq data, showing improved accuracy over existing methods in cancer TME analysis.
Shaoheng Liang, Jason A. Willis, Jinzhuang Dou…·Ken Chen
Sensei determines required sample sizes for detecting cell type abundance changes in single-cell studies using a beta-binomial model and t-test expansion.
Shaoheng Liang, Vakul Mohanty, Jinzhuang Dou…·Ken Chen
SCMER identifies non-redundant molecular features that delineate both common cell lineages and rare cellular states in single-cell data.