Author

Yunzi Guo

University of California, Irvine

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert R. La SpadaiD· 1 shared Anastasia Gromova· 1 shared Audrey S. DickeyiD· 1 shared Byeonggu Cha· 1 shared Christopher Karma· 1 shared Deavin Tendean· 1 shared Jacob DeyelliD· 1 shared Jonathan HasselmanniD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Albert R. La SpadaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintDec 19, 2025

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob Deyell, Jonathan Hasselmann, Linda Stroud…·Albert R. La Spada

This study shows PPARδ activation in microglia reduces inflammation and enhances phagocytic function, shifting microglia toward a disease-associated state in neurodegenerative models.

DOI 10.64898/2025.12.17.692628

mousebulk RNA-seq

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