Molecular BiologyCommunications BiologyPeer-reviewed
ppGpp functions as an alarmone in metazoa
Doshun Ito, Hinata Kawamura, Akira Oikawa…·Shinji Masuda
This study detects ppGpp in Drosophila and human cells and shows it induces metabolic changes, cell death, and lethality in Drosophila, establishing its role as an alarmone in metazoans.
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