Author

Yvan Boublik

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Audrey SirventiD· 3 shared Serge RocheiD· 3 shared Dana NaimiD· 2 shared Florent Cauchois· 2 shared Julie NguyeniD· 2 shared Kevin Espie· 2 shared Valérie Simon· 2 shared Alejandro FernándeziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

Audrey SirventORCID

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Author profile →

3 papers

Recent·Most cited

Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

Dana Naim, Zouheir HOUHOU, Florent Cauchois, Kevin Espie, Valérie Simon, Yvan Boublik, Francina Langa Vives, Zeinab Homayed, Conception Paul, Morgan Maillard, Michael Hahne, Julie Pannequin, Julie Nguyen, Audrey Sirvent, Serge Roche

This study identifies SLAP as a tumor suppressor that limits SFK activity in colonic epithelial cells, preventing tumorigenesis and hyperproliferation.

eLife · Sep 8, 2026Peer-reviewedCell Biology

Lipid-driven SRC self-association modulates its transformation capacity

Irrem-Laareb Mohammad, Marina Inés Giannotti, Elise Fourgous, Yvan Boublik, Alejandro Fernández, Anabel‐Lise Le Roux, Audrey Sirvent, Marta Taulés, Serge Roche, Miquel Pons

The paper shows lipid-mediated self-association of Src kinase forms condensates on lipid bilayers, modulating its transforming capacity through a lysine cluster in the SH4 domain.

Life Science Alliance · Mar 13, 2025Peer-reviewedMolecular Biology

SLAP controls mTORC2 integrity via UBE3C-mediated mLST8 ubiquitination to mediate its tumour suppressive function in colorectal cancer

Rudy Mevizou, Dana Naim, Florent Cauchois, Cécile Naudin, Georgia Greaves, Kevin Espie, Bastien Felipe, Valérie Simon, Yvan Boublik, Julie Nguyen, Serge Urbach, Serge Roche, Audrey Sirvent

This study identifies SLAP as a tumor suppressor in colorectal cancer that regulates mTORC2 integrity through UBE3C-mediated mLST8 ubiquitination, reducing mTORC2-AKT signaling.

bioRxiv · Mar 10, 2025 · PreprintCancer Biology