Julie Pannequin

This study identifies SLAP as a tumor suppressor that limits SFK activity in colonic epithelial cells, preventing tumorigenesis and hyperproliferation.

This study identifies a non-catalytic role for Rad18 in sustaining glioblastoma proliferation and proposes it as a therapeutic target.

This study shows that tumor cell viscosity affects their ability to circulate and extravasate, influencing metastasis.

This study identifies miR-4745 as a regulator of cancer stem cell traits in colorectal cancer, showing it inhibits CSC self-renewal and chemoresistance by targeting KLC2.

This study designs and tests a PXR agonist-based PROTAC (JMV7048) that degrades PXR in cancer cells, reducing chemoresistance and delaying colon cancer relapse.

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

The paper shows tuft cells release acetylcholine to directly target helminth parasites in the gut, enhancing type 2 immunity.