Author

Conception Paul

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:wet-lab / biochemical assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Michael HahneiD· 4 shared Francina Langa VivesiD· 2 shared Ilaria CicaliniiD· 2 shared Valérie PinetiD· 2 shared Audrey SirventiD· 1 shared Bénédicte LemmersiD· 1 shared Bérengère Pradet‐BaladeiD· 1 shared Carsten JankeiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersCell Biology

Michael HahneORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

Dana Naim, Zouheir HOUHOU, Florent Cauchois, Kevin Espie, Valérie Simon, Yvan Boublik, Francina Langa Vives, Zeinab Homayed, Conception Paul, Morgan Maillard, Michael Hahne, Julie Pannequin, Julie Nguyen, Audrey Sirvent, Serge Roche

This study identifies SLAP as a tumor suppressor that limits SFK activity in colonic epithelial cells, preventing tumorigenesis and hyperproliferation.

eLife · Sep 8, 2026Peer-reviewedCell Biology

TTLL6-mediated Polyglutamylation of PurA Maintains Colonic Crypt Integrity

Vanessa Pires, Chloé Pangault, Conception Paul, Pascal Finetti, François Bertucci, Émilie Mamessier, Célia Jardin, Nuttanid Numnoi, Ilaria Cicalini, Damiana Pieragostino, Laura Lebrun, Carsten Janke, Stéphane Audebert, Jean‐Paul Borg, Krzysztof Rogowski, , Michael Hahne

This study identifies TTLL6 as a key polyglutamylase in the colon, showing its role in maintaining crypt integrity and preventing colon cancer progression.

bioRxiv · Dec 17, 2025 · PreprintCell Biology

Machine Learning-Based Drug Response Prediction Identifies Novel Therapeutic Candidates for Colorectal Cancer Cell Line KM-12

Cyrine Chanchabi, Conception Paul, Vincent Coulon, Ilaria Cicalini, Damiana Pierogostino, Sachin Vishwakarma, Saiveth Hernández-Hernández, Pedro J. Ballester, Michael Hahne

The paper uses machine learning to predict drug responses in colorectal cancer cells, identifying novel compounds with cytotoxic or cytostatic effects.

bioRxiv · Feb 24, 2025 · PreprintCancer Biology

The R2TP chaperone assembles cellular machineries in intestinal CBC stem cells and progenitors

Chloé Maurizy, Claire Abéza, Bénédicte Lemmers, Monica Gabola, Ciro Longobardi, Valérie Pinet, Marina Ferrand, Conception Paul, Julie Bremond, Francina Langa Vives, François Gerbe, Philippe Jay, Céline Verheggen, Nicola Tinari, Dominique Helmlinger, , Bérengère Pradet‐Balade

This study investigates the role of the R2TP chaperone in intestinal stem and progenitor cells, showing its critical function in proliferation and its association with poor colorectal cancer prognosis.

Nature Communications · Aug 10, 2021Peer-reviewedDevelopmental Biology