Cancer BiologybioRxivPreprint
Activation of the Anaphase Promoting Complex reverses multiple drug resistant cancer
T. Aranson, V. MacDonald-Dickinson, G. F. Davies…·T. A. A. Harkness
This study shows that activating the Anaphase Promoting Complex (APC) in dogs with multiple drug resistant lymphoma reduces MDR biomarkers and restores chemosensitivity, suggesting APC as a therapeutic target.
DOI 10.1101/2020.05.26.115337