Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
G. Jacquemin, A. Wurmser, M. Huyghe, W. Sun, Z. Homayed, C. Merle, F. Qasrawi, M. Perkins, S. Richon, F. Dingli, G. Arras, D. Loew, D. Vignjevic, J. Pannequin, S. Fre
This study identifies THBS1-YAP signaling as a paracrine mechanism that reprograms healthy intestinal epithelial cells to support tumor growth.
bioRxiv · Dec 16, 2020Cancer Biology