Author

S. Fre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. Jacquemin· 4 shared B. Lloyd-Lewis· 2 shared C. Merle· 2 shared M. Huyghe· 2 shared M. Perkins· 2 shared A. Bore· 1 shared A. Velds· 1 shared A. Walczak· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersCell Biology

G. Jacquemin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

J. Urbanus, J. Cosgrove, J. Beltman, Y. Elhanati, R. De Andrade Moral, C. Conrad, J. Van Heijst, E. Tubeuf, A. Velds, L. Kok, C. Merle, J. P. Magnusson, J. Frisen, S. Fre, A. Walczak, , L. Perie

This study uses an in situ lineage tracing method to show that aging increases the number of HSPCs contributing to myelopoiesis, not their individual output.

bioRxiv · Dec 6, 2022 · PreprintImmunology

In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/Beta-catenin activation

B. Lloyd-Lewis, F. Gobbo, M. Perkins, G. Jacquemin, M. M. Faraldo, S. Fre

This study uses in vivo imaging to show that Wnt/Beta-catenin activation in mammary epithelial lineages leads to hyperplastic lesions and squamous transdifferentiation.

bioRxiv · Jun 22, 2021Cell Biology

Longitudinal high-resolution imaging through a flexible intravital imaging window

G. Jacquemin, M. Benavente-Diaz, S. Djaber, A. Bore, V. Dangles-Marie, D. Surdez, S. Tajbakhsh, S. Fre, B. Lloyd-Lewis

This study presents a versatile, fully flexible imaging window that acts as an implantable transparent second skin for small laboratory animal in vivo imaging.

bioRxiv · Feb 24, 2021Cell Biology

Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme

G. Jacquemin, A. Wurmser, M. Huyghe, W. Sun, Z. Homayed, C. Merle, F. Qasrawi, M. Perkins, S. Richon, F. Dingli, G. Arras, D. Loew, D. Vignjevic, J. Pannequin, S. Fre

This study identifies THBS1-YAP signaling as a paracrine mechanism that reprograms healthy intestinal epithelial cells to support tumor growth.

bioRxiv · Dec 16, 2020Cancer Biology

Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells.

L. Mourao, G. Jacquemin, M. Huyghe, W. J. Nawrocki, N. Menssouri, N. Servant, S. Fre

The paper identifies Notch1-expressing cells in intestinal tumors as a distinct population of cancer stem cells with properties similar to intestinal stem cells but reduced Lgr5 expression.

bioRxiv · Jul 9, 2018Cancer Biology