BiophysicsbioRxiv
Ligand-induced changes in dynamics mediate long-range allostery in the lac repressor
A. Glasgow, H. T. Hobbs, Z. R. Perry…·T. Kortemme
This study uses HDX/MS to show ligand-induced changes in dynamics mediate long-range allostery in the lac repressor, revealing flexibility differences in secondary structures across functional states.
DOI 10.1038/s41467-023-36798-1