Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical Investigations
M. Farokhnia, S. L. Deschaine, A. Gregory-Flores, L. J. Zallar, Z.-B. You, H. Sun, D. M. Harvey, R. C. N. Marchette, B. J. Tunstall, B. K. Mani, J. E. Moose, M. R. Lee, E. Gardner, F. Akhlaghi, M. Roberto, , L. Leggio
This study investigates how alcohol affects the ghrelin system in humans and rats, finding that ethanol reduces peripheral ghrelin levels without involving the ghrelin receptor or GOAT enzyme, and not proportionally to caloric intake.
bioRxiv · Jul 30, 2020 · PreprintPhysiology