BioinformaticsbioRxivPreprint
Rigidity-Aware Geometric Pretraining for Protein Design and Conformational Ensembles
Zhanghan Ni, Yanjing Li, Zeju Qiu…·Shengchao Liu
This paper introduces RigidSSL, a geometric pretraining framework for protein design and conformational modeling, improving designability and capturing realistic dynamics.
DOI 10.64898/2026.03.02.708991