BioengineeringbioRxivPreprint
Human skin fibrosis with iPSC-derived organoids reveals RUNX2-mediated fibroblast reprogramming
Jasim Khan, Sarmad Mehmood, Fuad Al Abir…·Lin Jin
This study uses human iPSC-derived skin organoids to model fibrosis, identifies RUNX2 as a key driver, and finds a small molecule that suppresses fibrotic programs.