Chander Raman

This study uses human iPSC-derived skin organoids to model fibrosis, identifies RUNX2 as a key driver, and finds a small molecule that suppresses fibrotic programs.

This study identifies metabolic dysregulation of autophagy in HS, linking mTOR activation and cadaverine to inflammation, pain, and malodor.

This study identifies expanded NKT and NK cells with elevated CD2 in HS lesions and shows CD2 blockade reduces inflammation and fibrosis.