MicrobiologybioRxivPreprint
Synergistic interactions of mobile genetic elements shape the stepwise evolution of multidrug-resistant plasmids
Yuqing Mao, Guorui Zhang, Zhou Han…·Thanh H. Nguyen
This study shows how mobile genetic elements synergistically drive the stepwise accumulation of antibiotic resistance genes in plasmids, proposing a framework to predict and surveil multidrug resistance.
DOI 10.1101/2025.11.28.691237