NeurosciencebioRxivPreprint
Multi-Timescale Neural Adaptation Failure as a Mechanistic Signature of Major Depression
Yun Hui Yang, Yanli Zhao, Kun Xie…·Dandan Zhang
This paper identifies neural adaptation failure as a core mechanism of major depression, showing it outperforms traditional measures in classification and provides a scalable biomarker.
DOI 10.64898/2025.12.16.694510