Thomas Gutsmann

This paper investigates how environmental conditions influence the structural assembly and cytotoxic function of the Staphylococcus aureus virulence peptide PSM1, revealing condition-dependent polymorphic structures and their role in host-cell interactions.

The paper shows that Plasmodium falciparum-infected red blood cells alter gene expression in brain endothelial cells, activating immune and antiviral pathways, and increasing cytokine and angiogenesis-related genes.

This study identifies synthetic peptide mimics that kill Candida albicans and synergize with caspofungin to prevent infection, showing efficacy in vitro and in vivo without resistance development.