Author

Christoph M. Dehnhardt

Xenon Pharmaceuticals (Canada)ORCID 0000-0001-5213-6354Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Alison J CuttsiD· 1 shared Alla Zenova· 1 shared Andrea Lindgren· 1 shared Angela Hussainkhel· 1 shared Celine M. Dubé· 1 shared Charles J. Cohen· 1 shared Elaine Chang· 1 shared Fiona L. ScottiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alison J CuttsORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyBritish Journal of PharmacologyPeer-reviewedJun 24, 2024

NaV1.6 inhibition drives the efficacy of voltage-gated sodium channel inhibitors to prevent electrically induced seizures in both wild type and Scn8aN1768D/+ gain-of-function mice

James P. Johnson, Thilo Focken, Parisa Karimi Tari…·James R. Empfield

The paper shows that inhibiting NaV1.6 reduces seizures in both wild-type and Scn8aN1768D/+ mice, suggesting NaV1.6 is a key target for anti-seizure drugs.

9 citations

mouseelectrophysiology

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