Author

Lucas-Raphael Müller

European Molecular Biology LaboratoryORCID 0000-0001-5312-9551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:dimensionality reduction· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Jonas RiesiD· 2 shared Arthur Jaques· 1 shared Boris FerdmaniD· 1 shared Christian KarrasiD· 1 shared Dafei XiaoiD· 1 shared Hao Sha· 1 shared Jakob H. MackeiD· 1 shared Jianwei CheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Jonas RiesORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 26, 2026

Multi-channel high-density single-molecule localization

Hao Sha, Lucas-Raphael Müller, Nestor Miguel Castillo Duque de Estrada…·Jonas Ries

This paper introduces DECODE-Plex, a deep learning framework for multi-channel single-molecule localization microscopy, improving imaging speed and quality in dense, overlapping data.

DOI 10.64898/2026.07.24.740199

imagingdeep learning

𝕏 PostBluesky

BiophysicsNature MethodsPeer-reviewedJun 1, 2024

Universal inverse modelling of point spread functions for SMLM localization and microscope characterization

Sheng Liu, Jianwei Chen, Jonas Hellgoth…·Jonas Ries

This paper introduces uiPSF, a toolbox to infer accurate PSF models from microscopy data for improved SMLM imaging and microscope characterization.

66 citationstop 1%

imagingfluorescence / live-cell microscopy

𝕏 PostBluesky