Chen-Jun Guo

This study shows KH0 and KH1 domains of FMR1 work together in m6A binding and phase separation, linking these processes to Fragile X Syndrome pathology.

This study identifies CTP as a regulator of hCTPS1 filamentation, revealing its structural basis and evolutionary conservation.

This study determines the structure of E. coli CTPS filament and identifies regulatory mechanisms, revealing a solvent-accessible ammonia tunnel and distinct CTP binding mode.

This study identifies a filament structure in Arabidopsis thaliana P5CS2 that facilitates substrate channeling, enhancing catalytic efficiency in proline synthesis under abiotic stress.