BioengineeringACS Chemical NeurosciencePeer-reviewed
De novo design of a β-helix tau protein scaffold: An oligomer-selective vaccine immunogen candidate for Alzheimer's disease
Adekunle Aina, Shawn C. C. Hsueh, Ebrima Gibbs…·Steven Samuel Plotkin
This paper designs a β-helix tau protein scaffold that mimics toxic tau oligomers and shows selective binding to antibodies, suggesting it could be an effective vaccine immunogen for Alzheimer's disease.
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