Author

Caroline J. Sheeba

Imperial College LondonORCID 0000-0001-5357-4743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

Peter SarkiesiD· 2 shared Anke KonradiD· 1 shared Joanna KrwawicziD· 1 shared Katie Hains· 1 shared Skirmantas KriaučionisiD· 1 shared Terry C. McMahoniD· 1 shared Toni BeltraniD· 1 shared Tony BélicardiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Peter SarkiesORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 13, 2024

Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage

Joanna Krwawicz, Caroline J. Sheeba, Katie Hains…·Peter Sarkies

This study shows that introducing 5mC into E. coli increases sensitivity to oxidative stress and alkylating agents due to reactive oxygen species and DNA damage.

DOI 10.1101/2024.09.13.612259

E. coliDNA methylation

𝕏 PostBluesky

Molecular BiologyBMC BiologyPeer-reviewedNov 6, 2020

Long-term experimental evolution reveals purifying selection on piRNA-mediated control of transposable element expression

Ulfar Bergthorsson, Caroline J. Sheeba, Anke Konrad…·Peter Sarkies

This study shows that natural selection in C. elegans maintains low TE expression, with increased TE expression observed in smaller populations due to reduced silencing efficiency.

13 citations

C. elegansDNA methylation

𝕏 PostBluesky