Cancer BiologyJournal of Experimental & Clinical Cancer ResearchPeer-reviewed
A high-content screen identified ingenol-3-angelate as an enhancer of B7-H3-CAR T cell activity by increasing B7-H3 protein expression on the target cell surface via protein kinase C alpha activation
Ha Won Lee, Carla O'Reilly, Alexandra Beckett…·Christopher C. DeRenzo
The paper identifies ingenol-3-angelate as a drug that enhances B7-H3-CAR T cell activity by increasing B7-H3 protein expression on target cells through protein kinase C alpha activation.
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