Korak Kumar Ray

The paper shows that mouse metaphase chromosomes from different cell types have distinct biomechanical properties, with ESC-derived chromosomes showing conserved force-dependent responses but differing from those of NSCs and preB cells.

This study shows ANKLE1 is a tension-stimulated endonuclease that cleaves DNA branchpoints under high tension, aiding in resolving interchromosomal bridges during mitosis.

DeepDiffusion detects heterogeneous diffusion in single-molecule trajectories using a physics-informed neural network, accurately identifying subtle changes despite large errors.

This study shows an ultra-stable RNA stem-loop samples multiple conformations and adapts its flexibility to fold efficiently and resist unfolding.

This study uses smFRET to analyze the conformational changes of RF2 on the ribosome, revealing structural rearrangements essential for polypeptide release and potential antibiotic targets.

This paper introduces tMAVEN, a software platform for analyzing single-molecule data using multiple kinetic models to improve accuracy by addressing mismatches between models and molecular mechanisms.

This paper introduces a new resolution metric for structural biology that quantifies how effectively biomolecular structural information is captured across different length scales.