Cristina Januário

This paper evaluates HMW fractionation as a complementary proteomics approach to identify serum biomarkers for neurodegenerative diseases, showing improved discrimination compared to direct serum analysis.

This study investigates mitochondrial dysfunction and redox changes in early Huntington disease stages using human and mouse models, showing increased mitochondrial activity and altered morphology.

This study shows that Huntington's Disease leads to increased release of mitochondrial components via extracellular vesicles due to mitochondrial and lysosomal dysfunction.