Author

Moritz Otto

University of CologneORCID 0000-0001-5407-373XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Organism:Arabidopsis· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Thomas WieheiD· 2 shared Paul GrablowitziD· 1 shared Yichen ZhengiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersEvolutionary Biology

Thomas WieheORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintAug 21, 2025

Inferring the history of gene copy number evolution

Moritz Otto, Thomas Wiehe

The paper introduces a model to infer gene copy number evolution history using copy number counts, applied to NLR genes in A. thaliana to estimate duplication events.

DOI 10.1101/2025.08.21.671444

ArabidopsisDNA methylation

𝕏 PostBluesky

Evolutionary BiologyHuman Genome VariationPeer-reviewedSep 23, 2024

Detecting adaptive changes in gene copy number distribution accompanying the human out-of-Africa expansion

Moritz Otto, Yichen Zheng, Paul Grablowitz, Thomas Wiehe

The paper investigates whether gene copy number distribution changes in European and Asian populations during the human out-of-Africa expansion are due to demographic factors or adaptive selection.

5 citations

humanwhole-genome sequencing

𝕏 PostBluesky