Meera Unnikrishnan

This paper introduces a hydrogel-based biosensor that accelerates bacterial interaction with reporter molecules through engineered transport, achieving faster and more accurate detection of infections and antimicrobial susceptibility.

This paper develops mannose-functionalized nanoparticles loaded with rifampicin to target macrophage-associated mycobacteria, showing improved efficacy and reduced toxicity in preclinical models.

The paper shows bacterial growth in agarose hydrogels is mainly affected by gel stiffness, water loss, and electrostatic interactions, not nutrient content.

This study shows that the staphylococcal type VII secretion system delays macrophage cell death during infection, enhancing bacterial survival.

This study shows Bacteroides species inhibit C. difficile toxin production through cross-feeding proline in mixed biofilms, revealing a mechanism for microbiota-mediated control of CDI.

This study shows that the host circadian clock modulates Staphylococcus aureus invasion into epithelial cells via the SraP-GP340 pathway.

This study shows that the T7SS effector EsxC in S. aureus affects daptomycin sensitivity by modulating cell membrane integrity.