Author

Xue‐Yan He

Washington University in St. LouisORCID 0000-0001-5423-5997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Mikala EgebladiD· 3 shared Camila O. dos SantosiD· 2 shared Adrian R. KraineriD· 1 shared Aktan AlpsoyiD· 1 shared Allison C. Schier· 1 shared Amelia Aumalika Biswas· 1 shared Amritha Varshini Hanasoge SomasundaraiD· 1 shared Ansuman T. SatpathyiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Mikala EgebladORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 23, 2026

FAK Inhibition Remodels the Metastatic ECM and Restores CD8+ T Cell Trafficking and Immunosurveillance

Nicole D. Barth, Bo Peng, Michael Papanicolaou…·Valerie G. Brunton

This paper shows that FAK inhibition remodels the metastatic ECM, enhancing CD8+ T cell infiltration and immunosurveillance in breast cancer.

DOI 10.64898/2026.01.21.700837

mouseproteomics

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Cancer BiologyNature GeneticsPeer-reviewedJun 17, 2024

Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma

Diogo Maia-Silva, Patrick J. Cunniff, Allison C. Schier…·Christopher R. Vakoc

The paper identifies MED12-p63 interaction as a driver of basal identity in PDAC through genetic screens and biochemical analysis.

19 citations

humangenetic perturbation / CRISPR

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Developmental BiologybioRxivPreprintFeb 5, 2024

Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1

Samantha Henry, Steven Macauley Lewis, Samantha L. Cyrill…·Camila O. dos Santos

This study shows that unresolved urinary tract infection leads to mammary tissue changes via collagen deposition and TIMP1, mediated by systemic host response.

DOI 10.1101/2024.02.05.578977

mousebulk RNA-seq

𝕏 PostBluesky