Anjana Badrinarayanan

The paper shows DNA supercoiling selectively enhances productive homology search by RecA filaments in Caulobacter crescentus, independent of DNA compaction.

The paper identifies intrinsic promoter strength as a key factor determining the temporal hierarchy of SOS response gene activation in Caulobacter crescentus, beyond LexA repressor properties.

This study shows that mitochondrial dysfunction in a novel mouse model impairs early lineage specification and embryonic development, highlighting mitochondrial roles in developmental transitions.

The paper tracks replisomes in Caulobacter crescentus to show replication elongation rates slow with nutrient limitation, contributing to cell cycle delays without increasing mutagenesis.

The paper investigates how mtDNA damage affects polymerase gamma activity and mtDNA stability in yeast, showing that exonuclease activity drives damage-induced mtDNA clearance.

The paper identifies a conserved bacterial transcription factor, Cada2, that mediates a methylation-dependent DNA damage response distinct from the SOS response.

This study investigates the evolutionary distribution of bacterial non-homologous end joining (NHEJ) through comparative genomics and phylogenetic analysis across 6000 genomes, finding it is sporadic and correlated with genome size and growth rate.