Matthew J. McLeod

The paper examines how small temperature variations in enzyme activation parameters affect Arrhenius/Eyring modeling, leading to apparent enthalpy-entropy compensation and misinterpretation of kinetic data.

The paper uses multi-temperature X-ray crystallography to show how temperature-dependent structural changes in enzyme complexes affect activity and challenge assumptions of Arrhenius/Eyring model parameters.

This study uses cryocrystallography to show ice forms more during warming than cooling in bovine oocytes, and suggests reducing CPA concentrations and increasing warming rates can eliminate ice formation.