Author

Nicholas J. Bradshaw

University of RijekaORCID 0000-0001-5581-8828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Beti ZaharijaiD· 2 shared Alfredo Ortega‐AlonsoiD· 1 shared Amanda B. ZheutliniD· 1 shared Bobana SamardžijaiD· 1 shared Éva RenneriD· 1 shared Jaana SuvisaariiD· 1 shared Jari K. HaukkaiD· 1 shared Jouko K LönnqvistiD· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Beti ZaharijaORCID

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3 papers

Recent·Most cited

Cell BiologyProgress in Neuro-Psychopharmacology and Biological PsychiatryPeer-reviewedDec 20, 2023

Aggregation of Disrupted in Schizophrenia 1 arises from a central region of the protein

Beti Zaharija, Nicholas J. Bradshaw

This study identifies a specific 30-amino-acid region in DISC1 critical for its aggregation, revealing two distinct mechanisms for DISC1 aggregation in mental illness.

8 citations

humanproteomics

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NeuroscienceCellsPeer-reviewedJul 13, 2023

Co-aggregation and parallel aggregation of specific proteins in major mental illness

Bobana Samardžija, Maja Juković, Beti Zaharija…·Nicholas J. Bradshaw

The paper investigates co-aggregation and parallel aggregation of specific proteins in major mental illness by analyzing brain samples and cell culture experiments.

9 citations

humanproteomics

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GeneticsOpen BiologyPeer-reviewedNov 1, 2017

The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to MicroRNA-484

Nicholas J. Bradshaw, Liisa Ukkola‐Vuoti, Maiju Pankakoski…·William Hennah

The paper investigates how genetic variation at the NDE1 locus affects gene expression and treatment response to psychiatric medications through interactions with microRNA-484 and CYP2C19.

17 citations

humanbulk RNA-seq

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