Author

Christopher J. Hosford

Cornell UniversityORCID 0000-0001-5756-6505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Joshua S. ChappieiD· 2 shared Anthony Q. BuiiD· 1 shared Carl J. SchiltziD· 1 shared Carolyn Court· 1 shared David MoragaiD· 1 shared Donald L. Court· 1 shared Emerson Ricardo SantiagoiD· 1 shared Hao PaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Joshua S. ChappieORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 1, 2026

Structural characterization the LlaI anti-phage defense system reveals insights into the evolution of nucleotide specificity and the organization of DNA binding in McrBC restriction complexes

Anthony Q. Bui, Christopher J. Hosford, Yiming Niu…·Joshua S. Chappie

The paper reports crystal structures of LlaI components, revealing nucleotide specificity evolution and DNA binding mechanisms in McrBC restriction complexes.

DOI 10.64898/2026.08.31.748284

bacteria (other)structural biology

𝕏 PostBluesky

MicrobiologyNucleic Acids ResearchPeer-reviewedMar 12, 2024

The crystal structure of bacteriophage lambda RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins

Myfanwy C. Adams, Carl J. Schiltz, Jing Sun…·Joshua S. Chappie

This paper presents the crystal structure of bacteriophage lambda RexA, revealing its DNA binding properties and evolutionary insights into phage exclusion mechanisms.

6 citations

E. coliprotein structure

𝕏 PostBluesky