Renee E. Oles

This paper introduces LRQ, a long-read metagenomics method that enables absolute strain abundance measurement and resolves microbial evolution in a Crohn's disease patient over eight years.

The paper analyzes gut microbiome data from three countries to show diet-microbiota associations vary by location and strain.

This study identifies genetic factors enabling Bacteroides fragilis to transition from commensal to pathogenic by analyzing 813 strains and their genomic diversity.

MicrobeMASST identifies microbial-derived metabolites and their producers using taxonomically-informed mass spectrometry data without prior knowledge.

This study identifies a bacterial sialidase, NanH, in Bacteroides fragilis that mediates early gut colonization and resilience through host-derived glycans.

This study compares the pangenome of Bacteroides fragilis genomospecies to reveal genetic diversity and ecological roles, finding division I and II strains represent distinct species with different functional adaptations.