Lukáš Trantı́rek

The paper demonstrates the presence of G-quadruplex structures in human blood plasma through experimental validation using synthetic and native nucleic acid samples.

The paper uses in-cell NMR to study DNA i-motif formation in human cells, finding that i-motifs are rare and cell cycle-dependent.

The paper identifies protein-protein interactions in the BCR-ABL signaling complex and shows that targeting these interactions could be a strategy for treating CML.