Author
University of RochesterORCID 0000-0001-5948-6744Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Ruiyue Tan, Margaret Hoare, Philip M. Bellomio…·Sina Ghaemmaghami
This study shows that formylation of initiator methionines enhances their enzymatic reduction and mitigates oxidation-related misprocessing.
Margaret Hoare, Ruiyue Tan, Isabella Militi…·Sina Ghaemmaghami
The paper describes a method to enzymatically synthesize isotopically labeled hydrogen peroxide (H218O2) for use in mass spectrometry to accurately measure methionine oxidation levels.
Margaret Hoare, Ruiyue Tan, Kevin A. Welle…·Sina Ghaemmaghami
This paper introduces MObBa, a mass spectrometry method to quantify methionine oxidation by alkylating unoxidized methionines, enabling accurate measurement of oxidation levels in peptides and proteomes.