Louis Lambrechts

This study shows that a non-retroviral EVE suppresses viral replication in mosquitoes across life stages and generations but does not affect survival or reproduction.

The paper examines DENV infection in Aedes aegypti mosquito brains and finds minimal transcriptional response despite productive viral replication.

This paper presents a targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti, showing it can replicate WGS population structure analyses and accurately measure genetic admixture.

This study uses deep learning to analyze mosquito behavior changes after infection, finding species-specific effects that could impact disease transmission.

The paper identifies polygenic viral factors in African Zika virus strains that enhance mosquito transmission efficiency compared to Asian strains.

This study identifies a cytochrome P450 gene variant that influences dengue virus susceptibility in Aedes aegypti mosquitoes.

This study identifies a naturally occurring salivary gland barrier in NAK Ae. aegypti mosquitoes that significantly reduces ZIKV transmission potential, offering a new strategy for vector control.

This study challenges the assumed antiviral role of Vago genes in Aedes aegypti by showing that VLG-1 has a modest proviral effect during DENV and ZIKV infections.

This paper introduces BuzzWatch, a platform to monitor mosquito behavior over weeks, revealing differences in activity patterns and responses to environmental and physiological factors.

The study investigates the role of the siRNA pathway in regulating transposable element expression in Aedes aegypti, finding limited impact in both somatic and gonadal tissues.

The paper identifies novel persistent viruses in Aedes aegypti mosquitoes using small RNA sequencing and confirms their replication and transmissibility in cell lines.

This study investigates dengue virus susceptibility in African Aedes aegypti populations and finds significant variation and strain-specific interactions.

This study compares transposable element organization in the large Aedes aegypti genome to smaller Diptera genomes, finding higher TE transposition and lower elimination rates in Ae. aegypti.

The paper presents an improved Aedes aegypti genome assembly, AaegL5, which enhances biological understanding and vector control efforts by resolving key genomic features and identifying new targets for intervention.

The paper compares the midgut bacterial microbiome of geographically diverse Aedes aegypti colonies reared in the same insectary, finding they are similar, suggesting microbiota is environmentally determined.