Author

Rajeswari Appadurai

Indian Institute of Science Education and Research, TirupatiORCID 0000-0001-5988-868XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Anand Kumar SrivastavaiD· 2 shared Irawati RoyiD· 2 shared Anand SrivastavaiD· 1 shared Ashok SekhariD· 1 shared Harikrishnan Venkatesh· 1 shared Sangeetha BalasubramanianiD· 1 shared Vijay SubramanianiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

Anand Kumar SrivastavaORCID

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3 papers

Recent·Most cited

BiophysicsProtein SciencePeer-reviewedAug 15, 2025

Unambiguous assignment of kinked beta sheets leads to insights into molecular grammar of reversibility in biomolecular condensates

Irawati Roy, Rajeswari Appadurai, Anand Kumar Srivastava

The paper introduces a machine learning method to unambiguously identify kinked beta sheets in protein structures and demonstrates its application in analyzing prion-like proteins.

2 citations

protein structuredeep learning

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BiophysicsJournal of Biological ChemistryPeer-reviewedApr 8, 2025

hnRNPA1 RGG-box acts a "catalyst" in UP1-induced destabilization of RNA and DNA telomeric G-Quadruplexes

Sangeetha Balasubramanian, Irawati Roy, Rajeswari Appadurai, Anand Srivastava

This study investigates how the RGG-box of hnRNPA1 interacts with telomeric G-quadruplexes, showing it preferentially binds to specific structures and can destabilize them, aiding hnRNPA1-UP1 in telomere maintenance.

8 citations

DNA methylationproteomics

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BioinformaticsbioRxivPreprintFeb 13, 2025

Morpheus: A fragment-based algorithm to predict metamorphic behaviour in proteins across proteomes

Vijay Subramanian, Rajeswari Appadurai, Harikrishnan Venkatesh…·Anand Kumar Srivastava

Morpheus predicts fold-switching proteins by analyzing structural fragments across proteomes, identifying 10% of proteins with metamorphic behavior.

2 citations

protein structurestatistical model

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