Author

Joseph Elsherbini

Ragon Institute of MGH, MIT and HarvardORCID 0000-0001-5995-2936Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:deconvolution· 1

Frequent Co-Authors

Caroline M. MitchelliD· 3 shared Douglas S. KwoniD· 3 shared Jiawu XuiD· 3 shared Seth M. BloomiD· 2 shared Aakanksha GulatiiD· 1 shared Abidemi JunaidiD· 1 shared Alicia C. Jorgenson· 1 shared Amy DeikiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersPathology

Caroline M. MitchellORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PathologybioRxivPreprintNov 5, 2025

Synergistic therapeutic effects of endolysin BNT331 and a Lactobacillus crispatus consortium in a human vagina chip model of bacterial vaginosis

Aakanksha Gulati, Alicia C. Jorgenson, Ashleigh Williams…·Donald E. Ingber

Endolysin BNT331 combined with Lactobacillus crispatus reduces bacterial load and suppresses inflammation in a human vagina chip model of bacterial vaginosis.

DOI 10.1101/2025.11.05.686849

humanexperimental assay

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BioinformaticsbioRxivPreprintSep 4, 2025

kSanity: A k-mer based application forprecision bacterial strain detection andquantification

Michael France, Issac Chaudry, Joseph Elsherbini, Jacques Ravel

kSanity detects and quantifies bacterial strains in metagenomic data using k-mer matching, showing precision even at low coverage.

1 citation

bacteria (other)metagenomics

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BioinformaticsbioRxivPreprintAug 15, 2025

StrainFacts accurately quantifies both endogenous and live biotherapeutic product strain abundances in simulated and clinical vaginal microbiota samples

Johnathan B. Shih, Seth M. Bloom, Jiawu Xu…·Douglas S. Kwon

1 citation

humanmetagenomics

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MicrobiologyCellPeer-reviewedAug 19, 2024

Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment

Meilin Zhu, Matthew W. Frank, Christopher D. Radka…·Douglas S. Kwon

This study identifies oleic acid as a compound that inhibits L. iners and promotes L. crispatus growth, offering a potential new treatment strategy for bacterial vaginosis.

68 citationstop 1%

humanexperimental assay

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