Author

Shawn C. Owen

Medical College of WisconsinORCID 0000-0001-5996-7679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Randall Theodore PetersoniD· 2 shared Alexandria Van ScoykiD· 1 shared Anca FranziniiD· 1 shared Anthony D. PomicteriD· 1 shared Donald E. AyeriD· 1 shared Michael W. DeiningeriD· 1 shared Morgan C. Marsh· 1 shared Orlando Antelope· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Randall Theodore PetersonORCID

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2 papers

Recent·Most cited

BioengineeringPLoS ONEPeer-reviewedOct 29, 2026

A dCas9 Proximity Reporter for Investigating DNA Linear and Rotational Dynamics

Saba Parvez, Morgan C. Marsh, Shawn C. Owen, Randall Theodore Peterson

This paper develops a dCas9-based tool to measure DNA sequence proximity and orientation, finding that rotational alignment significantly affects dCas9 interactions.

DOI 10.1371/journal.pone.0355748

humanexperimental assay

𝕏 PostBluesky

BioengineeringCell chemical biologyPeer-reviewedNov 1, 2024

Bioluminescence Assay of Lysine Deacylase Sirtuin Activity

Alexandria Van Scoyk, Orlando Antelope, Anca Franzini…·Michael W. Deininger

The paper develops SIRTify, a bioluminescence assay to measure sirtuin activity by detecting lysine deacylation, showing it accurately reflects sirtuin specificity and modulator effects.

3 citations

proteomicsexperimental assay

𝕏 PostBluesky